San Francisco 49ers running back Isaac Guerendo is expected to return from foot and hamstring injuries and play Monday, a ...

As the 49ers look to play spoiler against the Lions on Monday Night Football, RB Isaac Guerendo got a positive injury update.

San Francisco 49ers running back Isaac Guerendo is expected to play Monday night against the Detroit Lions, according to ESPN ...

San Francisco 49ers running back Isaac Guerendo, sidelined for last Sunday's game against the Miami Dolphins due to hamstring ...

San Francisco 49ers running back Isaac Guerendo is expected to return from foot and hamstring injuries and play Monday, a ...

Guerendo (foot/hamstring) is expected to play Monday against the Lions, Adam Schefter of ESPN reports. The 49ers have yet to post their final Week 17 injury report, but he seems destined to be listed ...

Guerendo (foot/hamstring) doesn't have a designation for Monday's game versus the Lions, Cam Inman of The San Jose Mercury News reports.

As Brock Purdy celebrated his 25th birthday Friday, the 49ers struggled to field and coach up healthy offensive lineman ahead ...

San Francisco 49ers QB Brock Purdy discussed supporting the new offensive line and the team's mindset heading into their ...

As Brock Purdy celebrated his 25th birthday Friday, the 49ers struggled to field and coach up healthy offensive lineman ahead ...

A year ago, the 49ers beat the Lions in the NFC Championship at Levi's Stadium. What a difference a year makes. On Thursday, ...

The 49ers have been without Isaac Guerendo for most of December. But the RB helped provide a promising update Thursday.