NHS watchdog to review evidence on two pioneering Alzheimer’s drugs - Donanemab and lecanemab were licensed for use in the UK in 2024 but were not made available on the NHS after Nice deemed their ben ...

What has long been interpreted as permanent and irreversible vascular damage may not be exclusively so. In people with Down syndrome—one of the most robust populations for studying Alzheimer's disease ...

People carrying at least one APOE4 allele have a higher risk of Alzheimer's disease compared with APOE3/3 carriers; people with two APOE4 alleles have the highest risk. The APOE2 allele is associated ...

Older people with a genetic risk of Alzheimer's disease did not experience the expected increase in cognitive decline and dementia risk if they consumed relatively large amounts of meat.

The groups are calling for genotype-informed prevention and treatment strategies, APOE stratification in clinical trials, and related public policies.

Black Americans are nearly twice as likely as their white counterparts to develop dementia, and researchers have found that obesity may be a significant factor in accelerating cognitive decline, ...

Dr. Thomas Karikari, an Assistant Professor at the University of Pittsburgh, plays a key role in the creation of blood-based biomarkers for Alzheimer's disease. His pioneering study has influenced the ...

GLP-1 receptor agonist indications continue to expand beyond glycaemic and weight control, with benefits now shown in chronic kidney disease in type 2 diabetes, obesity-related heart failure, knee ...

New analyses show DLB patients with lower plasma pTau181 levels — indicating an earlier stage of disease and absence of Alzheimer’s disease (AD) co-pathology — experienced greater clinical benefit ...

Alzheimer’s disease affects millions of people around the world and is one of the leading causes of memory loss and cognitive ...

Smith Could a simple blood test predict your risk of getting dementia years, or even decades, before you experience memory ...

I’ve watched Alzheimer’s disease touch more families in Northwest Washington than most people realize. In my own family, we saw how quickly small lapses in memory can turn into something far more ...