San Francisco 49ers running back Christian McCaffrey scores his tenth touchdown of the 2025 NFL season, and second of the game, on a 9-yard reception ...

Arizona had the passing game working, but it didn't matter in a 41-22 loss to San Francisco at State Farm Stadium in Glendale ...

Brock Purdy threw three touchdown passes in his return from a toe injury, Christian McCaffrey had two rushing touchdowns and ...

What's the Arizona Cardinals vs San Francisco 49ers score? Follow our live score updates for latest news, highlights, ...

Follow along with live updates as the San Francisco 49ers begin a crucial four-game stretch starting in Arizona against the Cardinals.

The quarterback was slammed to the turf during their 35-6 loss to the Jaguars Saturday. Herbert has been sacked 35 times this season, more than any other quarterback in the NFL, through Week 11.

The San Francisco 49ers have had injuries on offense and defense all year, but now their special teams unit is dealing with ...

San Francisco 49ers QB Brock Purdy connected with TE George Kittle on a 4-yard touchdown pass, marking Kittle's 50th career ...

The Arizona Cardinals and San Francisco 49ers revealed their final inactives report for Week 11 - who's in, who's out?

In Week 11's game against the San Francisco 49ers, Garrett Williams went down with a shin injury, rolling in pain immediately after hitting the ground with 11:08 left in the third quarter. He is ...

The Kansas City Chiefs announced the injury status for offensive lineman Jaylon Moore hours before the game against the ...

The San Francisco 49ers are already without Fred Warner, and they may have lost another linebacker early against the Arizona ...