2025 Week 2 NFL score predictions, odds, top picks today
Digest more
Our insiders dove in on the aftermath of the Dolphins' disastrous opener, both New York QB situations and some RB fantasy nuggets ahead of Week 2.
Playing in a confidence pool and looking for advice? KC Joyner has you covered with Week 2 picks straight up and against the spread.
7hon MSN
NFL Week 2 picks and predictions, straight-up and ATS: Vikings ride the wave, Ravens bounce back
NFL picks for every Week 2 game with predictions straight-up and against the spread. The Vikings look to ride their momentum, the Ravens, Chiefs and many more aim to bounce back, and much more.
Matchups are the key to fantasy lineup decisions. Here are the most and least favorable for Week 2 at QB, RB, WR and TE.
Injuries are already biting the San Francisco 49ers after two of their top players were dinged up last week in the season-opening win over the Seattle Seahawks, yet the Niners are still 3-point favorites in Week 2.
1d
Sporting News on MSNNFL picks, predictions against the spread Week 2: Chiefs get Super revenge on Eagles, Steelers and Chargers stay hot
Learn more > Week 1 of the 2025 NFL season had its fair share of surprises, given almost every team is an unknown quantity with personnel and coaching until they take the field for the first time when it counts.
The first week of the NFL season is always the most chaotic, so let's try to make sense of what we saw and improve our fantasy rosters.