However, a post from ESPN's Adam Schefter also showcases that the Bills are tied with the Jacksonville Jaguars for the ninth-easiest schedule based on their opponents' 2024 winning percentage (.467).

The Buffalo Bills are one of the top contenders in the NFL, which has them being featured in several primetime games during the 2025 season.

Fresh off a heartbreaking loss to the Kansas City Chiefs in the AFC Championship Game last season, the Buffalo Bills are set to enter 2025 with Super Bowl aspirations.

Underscoring the entire schedule is that the 2025 campaign will be the last in their longtime home of Highmark Stadium, where they began playing in 1973. As their new stadium across the street is scheduled to be ready for the 2026 season, the Bills have one final chance to chase Super Bowl glory in their farewell season to their 53-year home.

After coming up short of the Super Bowl in 2024, there's a $30 million reason why the Bills opted against adding a new star WR1.

The season openers between the Dallas Cowboys and Philadelphia Eagles and Baltimore Ravens-Buffalo Bills and Detroit Lions-Green Bay Packers are among the most intriguing matchups to launch the 2025 NFL campaign.

It’s not as if Sean McDermott’s Buffalo Bills haven’t managed to solve Patrick Mahomes and the Chiefs. They just haven’t done it when it counted most.

Ravens linebacker Roquan Smith took one look at Baltimore's 2025 schedule and started licking his chops when seeing a Week 1 date with the Buffalo Bills, who ousted his team from the 2024 playoffs.