Cytochrome P450 enzymes constitute a vast and diverse superfamily of haem‐containing proteins that orchestrate a broad array of oxidative reactions. Their inherent versatility enables them to catalyse ...

Study reveals an important discovery in the realm of nanomachines within living systems. Prof. Sason Shaik from the Hebrew University of Jerusalem and Dr. Kshatresh Dutta Dubey from Shiv Nadar ...

The cytochrome P450 enzymes form a vast superfamily of haem‐containing monooxygenases that catalyse the metabolism of a broad spectrum of endogenous substances and xenobiotics. Their dynamic catalytic ...

An international research team, including scientists from the U.S. Department of Energy's (DOE's) National Renewable Energy Laboratory (NREL), has discovered and characterized a new family of ...

Mechanistically, the chemists think that in the presence of the enzyme, there’s a formal hydrogen atom abstraction that is ...

Enzymes, the micro machines in our cells, can evolve to perform new tasks when confronted with novel situations. But what if you want an enzyme to do an entirely different job -- one that it would ...

When agricultural weeds evolve resistance to herbicides, they do it in one of two ways. In target-site resistance, a tiny mutation in the plant's genetic code means the chemical no longer fits in the ...

Alexis Garcia, PharmD, senior director of business development at Tabula Rasa HealthCare, outlines how cytochrome P450 enzymes can impact medication efficacy in patients taking multiple drugs. So the ...

Scientists have solved a 40-year-old puzzle about the mysterious process by which a critical enzyme metabolizes nutrients in foods and chemicals in drugs such as Tylenol, caffeine and opiates. The ...

Editor’s note: This week’s Deep Dive feature focuses on human enzyme research. RESEARCH TRIANGLE PARK – It’s the biggest National Institutes of Health grant in Appalachian State University’s history, ...

Transgenic tobacco (Nicotiana tabacum cv Xanthi) plants expressing a genetically engineered fused enzyme between rat cytochrome P4501A1 (CYP1A1) and yeast NADPH-cytochrome P450 oxidoreductase were ...

An international research team, including scientists from the U.S. Department of Energy's (DOE's) National Renewable Energy Laboratory (NREL), has discovered and characterized a new family of ...