Figure 1: Cellular localization of CRF peptide, CRFR1 and CRFR2 in the nucleus accumbens. Figure 2: CRF increases dopamine release in the nucleus accumbens through coactivation of CRFR1 and CRFR2.

A new study on laboratory rats has found that the brain’s ability to learn from rewards is enhanced by the hormone estrogen.

A new study shows that estrogen naturally modulates dopamine signaling in the brain, altering how female rats learn reward cues across the reproductive cycle.

Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, No. 26 (Dec. 19, 1995), pp. 12304-12308 (5 pages) The nucleus accumbens is considered a critical target of the ...

Researchers at Johns Hopkins University School of Medicine have created a single-nucleus RNA-sequencing resource to generate molecular signatures of cell types in five key regions of the human brain ...

It only makes sense: Neuroscientists see a link between your drive to build a better reputation and the intensity of your Facebook usage. They say the two activities stimulate a reward center in the ...

Aims: A possible addiction mechanism has been represented by altered functional connectivity (FC) in the resting state. The aim of this study was to evaluate the FCs of the insula and nucleus ...

Social behavior in mouse models of autism spectrum disorder normalized when investigators triggered the release of a specific signaling substance, serotonin, in a single part of the animals' brains, ...