The matchups in a Week 1 NFL lineup that shouldn't be missed include the Detroit Lions squaring off against the Green Bay Packers at Lambeau Field. Here are the betting odds to dissect prior to Week 1 in the NFL.

NFC North rivals Minnesota (0-0) and Chicago (0-0) square off Monday Night in Chicago to close out Week 1 of the 2025 NFL season.

New DraftKings users can get a $200 bonus and over $200 off NFL Sunday Ticket to bet Bears vs. Vikings on Monday Night Football

Both quarterbacks have shined so far in this contest, as Rodgers sits with four passing touchdowns — each to a different receiver — while Fields has over 200 passing yards and two touchdowns of his own, including one passing and one rushing with the fourth quarter in progress.

With their 53-man roster set, the Denver Broncos are now ready to kick off their 2025 NFL schedule. Denver will begin the regular season at home when they host the Tennessee Titans at Empower Field at Mile High on Sunday,