The Cardinals have a number of players out for this game, as linebacker Mack Wilson was placed on injured reserve, receiver Marvin Harrison Jr. is out after having his appendix removed and cornerback Will Johnson is missing another game.

The 49ers are 3.5-point favorites, according to the latest 49ers vs. Cardinals odds. The over/under for total points scored is 48.5. Before making any 49ers vs. Cardinals picks, make sure you check out the NFL picks from the SportsLine Projection Model.

If the Cincinnati Bengals defense improved against the Pittsburgh Steelers, it wasn't enough improvement to avoid a third straight loss.

A big stretch of games begins for the San Francisco 49ers on Sunday in Arizona against the Cardinals. Here's how to watch their Week 11 showdown.

The Bengals look to bounce back from a pair of bad losses and beat the Pittsburgh Steelers to sweep the season series.