A melanocortin-4 receptor agonist did not induce significant decreases in BMI for patients with four rare genetic forms of ...

The non-receptor tyrosine kinase, focal adhesion kinase (FAK), can signal downstream of integrins and growth factor receptors 1. FAK is expressed ubiquitously and has essential roles in a number of ...

Oestrogen-induced DNA damage drives genomic instability in BRCA1 mutation cells, with dietary compounds showing protective potential.

Rhythm Pharmaceuticals (NASDAQ:RYTM) reported Phase 3 top-line results from its EMANATE trial evaluating setmelanotide in ...

Heterozygous familial hypercholesterolemia (HeFH) is a genetic disorder a person can inherit from a parent. It can cause a person to develop dangerously high cholesterol levels. HeFH affects how a ...

Homozygous deficiency of alpha 1-atitrypsin is known to predispose to pulmonary emphysema. Measurement of the trypsin inhibitory capacity (TIC) of serum specimens from 28 relatives of a homozygous ...

A randomized phase II trial of medical cannabis to reduce symptom burden in patients with newly diagnosed advanced pancreatic cancer (CanPan). This is an ASCO Meeting Abstract from the 2026 ASCO ...

Eliot Brinton, MD, opens a discussion surrounding the treatment landscape for patients with homozygous familial hypercholesterolemia (HoFH). Eliot Brinton, MD: I’m Dr Elliot Brinton. I’m the president ...

Heterozygous familial hypercholesterolemia (HeFH) is a monogenic disorder that affects about 1 in 500 people, with a higher prevalence in certain subpopulations such as people of Quebecois, Christian ...