IBD is an immune condition. Instead of peacefully coexisting with gut microbes, the immune system becomes overly reactive, ...

A new study indicates a common genetic variant may interact with gut bacteria to trigger chronic inflammation in ulcerative colitis. The findings may help explain why people experience the disease ...

Bacteria uses multiple defense mechanisms to survive in the host body. Shigella bacteria, that causes colitis, disable multiple host defense pathways using three specialized effector proteins, as ...

Diagram showing the mechanism discovered in the study. Inflammation of the intestines in ulcerative colitis results from an excessive helper Th2 immune response. Smoking leads to aromatic compounds ...

BERLIN — An individual’s profile of antibody responses to a range of herpes viruses and encapsulated bacteria such as Streptococcus could predict the onset of inflammatory bowel disease (IBD) up to 10 ...

Probiotics can help maintain a healthy gut microbiome or restore populations of 'good bacteria' after a heavy course of antibiotics. But now, they could also be used as an effective treatment strategy ...

Ulcerative colitis is more than a digestive condition — it’s a daily challenge of balancing symptoms, treatment, and mental well-being. New research is uncovering how genetics, gut bacteria, and ...

The human gut is home to trillions of bacteria that play vital roles in digestion, immunity, and overall health. Disruption of the interaction between the gut microbiome and the host can contribute to ...

Upon presentation to the emergency department (ED), the monocyte distribution width (MDW) derived from routine full blood examinations could effectively differentiate acute severe ulcerative colitis ...

Arthritis is the most common nonintestinal complication for people with ulcerative colitis (UC). These tips can help stave it ...

Researchers have identified a gut-genetic interaction that could trigger an overactive immune response in the colon — offering one possible explanation for the pain and bleeding of ulcerative colitis, ...