Despite the win against Louisville, head coach Dabo Swinney and the team will be without two key linemen for the final stretch of the regular season and postseason.

Clemson offensive lineman Brayden Jacobs suffered a season-ending injury after the Louisville game, per Dabo Swinney.

The Cardinals look to bounce back, and the Tigers are fighting to close with a flourish. Here’s the Clemson vs Louisville preview, prediction, and betting lines.

Here's how to watch the Clemson Tigers vs. No. 19 Louisville Cardinals, including TV info, streaming options, injury updates, betting odds, and key game details.

Clemson had lost 2 straight games with a bye week sandwiched in, so when it defeated the 1.5-point underdog Florida State Seminoles 24-10 (Under 57) last Saturday the victory marked the Tigers' first since Oct. 18. Clemson's 5 losses mark its most since coach Dabo Swinney ' s first season (2009).

Laura Ziegler finished with 17 points and 10 rebounds to lead No. 22 Louisville to a 65-54 victory over Clemson in an Atlantic Coast Conference opener.

Viewers will remember the performance that Louisville running back Isaac Brown had against the Clemson Tigers last season, but head coach Dabo Swinney may be se

The Clemson Tigers (8-5-5, 4-4-2 ACC) took down the Liberty Flames (14-4-4, 6-0-2 CUSA) in the first round of the NCAA Tournament Thursday night in Clemson, S.C. Elle Bissinger kicked the game off with her third career goal early in the first half,