"NFL 100 Greatest" counts down the top 100 game changers in NFL history, and former Detroit Lions running back and Pro Football Hall of Fame member Barry Sanders lands at No. 74.

Watch Detroit Lions running back Barry Sanders rush for over 200 yards and 4 TD in his greatest game ever.

In the new documentary ‘Bye Bye Barry,’ the legendary Detroit Lions running back explains why he retired from the brutal game on top.

Sanders was just 1,457 yards shy of Walter Payton’s NFL all-time rushing record when he unexpectedly walked away from the game.

NFL legend Barry Sanders on abrupt retirement, faith Barry Sanders talks to OutKick's Dan Dakich about why he retired from the NFL, seemingly with plenty left in the tank.

Legendary running back Barry Sanders wrote that “you can’t underestimate the impact” that Jim Brown had on the NFL. Brown died Thursday at 87.

Barry Sanders reveals why he retired from the NFL in his new Prime Video doc, Bye Bye Barry. Here's what to know about the Lions running back's retirement.

Sanders, a Hall of Fame running back and the greatest player in Lions history, has been tabbed as an honorary captain for Sunday's game against the San Francisco 49ers.